In Vampire: The Masquerade – Vendetta each player leads one of the Camarilla clans of Chicago, determined to gain enough influence to seize control of the city and become its new Prince.

Over three rounds, they will play cards and blood at several locations to gain control of powerful allies, both human and Kindred, earning influence and unlocking their special abilities. Players will also gain new cards at the beginning of each round, gaining new abilities to surprise their opponents.

At the end of the third round, the vampire with the most influence is the winner… and the new Prince of Chicago!